Tools for Managing Stress & Anxiety in 2025 — Dr Jonathan Kuo

Why are stress and anxiety climbing, and what can you do when breathing and meditation aren't enough? I sat down with Dr Jonathan Kuo, a double board-certified doctor who trained in anaesthesia and pain medicine and founded the longevity clinic Extension Health.

Jonathan explains the neck injection he calls the neuro reset and why he uses it for PTSD, how inflammation from poor sleep, ultra-processed food and blood sugar spikes can show up as anxiety, and why he says to hold off on the cold plunge after training. He walks me through his morning of meditation, sauna and six to ten peptides, why he gives some healthy patients small doses of GLP-1 drugs, and what he has seen from ketamine and guided psychedelic work.

We also cover why insurers still won't pay for prevention, and how AI could bring precision health to more people.